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Transfected Stable Cell Lines

TCF LEF Reporter HEK-293 Cell Line

  • For research use only

Cat No.

ABC-RC059F
Product Type

Reporter Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

HEK293
Source Organ

Kidney
Disease

Normal
Storage

Liquid Nitrogen

TCF LEF Reporter HEK-293 Cell Line enables Wnt pathway drug evaluation via luciferase readouts,ideal for pathway activation and signal transduction assays.

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  • TCF LEF Reporter HEK-293 Cell Line
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Home | Transfected Stable Cell Lines | Reporter Stable Cell Lines | TCF LEF Reporter HEK-293 Cell Line

Description

Wnt proteins are secreted lipid-modified glycoproteins that can activate different intracellular signaling pathways. They regulate cell growth, function, differentiation, and cell death, which are essential for normal embryo development. Dysregulation of Wnt signaling can lead to various diseases, including cancer.The TCF LEF Reporter HEK-293 Cell Line is a luciferase reporter cell line constructed based on the Wnt signaling pathway. Wnt proteins activate the Frz receptor, leading to the translocation of β-catenin into the nucleus where it binds to TCF/LEF transcription factor binding sites and activates downstream pathways, resulting in the expression of luciferase. Luciferase readings represent the activation effect of the signaling pathway and can therefore be used for evaluating the in vitro effects of Wnt pathway-related drugs.

Species

Human
Cat.No

ABC-RC059F
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

HEK293
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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