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| Species | Human |
| Cat.No | ABC-KC2225 |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 100ug |
| Shipping Info | Ice Pack |
| Growth Conditions | 37 ℃, 5% CO2 |
| Storage | Store UBA7 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. |
| Product Type | CRISPR Knockout Cell Lysate |
| Host Cell | A549 |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like IFN-stimulated gene 15 protein. [provided by RefSeq, Jul 2008]
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
For research use only