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Transfected Stable Cell Lines

USP18 Knockout Cell Lysate

  • For research use only

Cat No.

ABC-KC2268
Product Type

CRISPR Knockout Cell Lysate
Species

Human
Host Cell

A549
Storage

Store USP18 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.

Investigate USP18 Knockout Cell Lysate to explore ubiquitin-specific protease functions in immune regulation, antiviral defense, and protein stability.

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  • USP18 Knockout Cell Lysate
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Home | Transfected Stable Cell Lines | Knockout Cell Lysate | USP18 Knockout Cell Lysate

Description

The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to IFN, suggesting a function of this protein in downregulating IFN responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]

Species

Human
Cat.No

ABC-KC2268
Product Category Transfected Stable Cell Lines
Size/Quantity

100ug
Growth Mode

Adherent
Shipping Info

Ice Pack
Growth Conditions

37 ℃, 5% CO2
Storage

Store USP18 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles.
Product Type

CRISPR Knockout Cell Lysate
Host Cell

A549
Stock

Custom

Application

  • For research use only

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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