Vero Cells Derivation
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The 9-Mb deficiency on chromosome 12 was found by genome sequence analysis on Vero cells. This induces the loss of type 1 gene interferon gene cluster and cyclin-dependent kinase inhibitor CDKN2A and CDKN2B genes. Thus, Vero cells do not secrete interferon α or β, and are susceptible to virus infection like SV40 and bacterial toxins like diphtheria toxin and Shiga-like. However, the Vero cells still respond to recombinant interferon because they maintain interferon α or β receptor.
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Monkey Kidney Cell Lines
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