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Transfected Stable Cell Lines

Xpress™ Cyno GPC3 Over-expressing Cell Line (CHOK1)

  • For research use only

Cat No.

ABC-X0416C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Crab-eating macaque
Host Cell

CHOK1
Source Organ

Ovary
Disease

Normal
Storage

Liquid Nitrogen

The Xpress™ Cyno GPC3 over-expressing cell line (CHOK1) is ideal for cross-reactivity validation, antibody screening, and preclinical target assessment.

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  • Xpress™ Cyno GPC3 Over-expressing Cell Line (CHOK1)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Cyno GPC3 Over-expressing Cell Line (CHOK1)

Description

Cyno GPC3 CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. Cyno GPC3 CHOK1 overexpression cell line is generated by stable integration of exogenous cynomolgus monkey GPC3 into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
GPC3 (Glypican 3) is a membrane-bound heparan sulfate proteoglycan involved in Wnt signaling and cell proliferation. It is overexpressed in hepatocellular carcinoma and used as a biomarker and therapeutic target in liver cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Crab-eating macaque
Cat.No

ABC-X0416C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This cynomolgus model aids in cross-species validation of GPC3-targeted therapies, including antibody-drug conjugates and CAR-T cell products, facilitating translational safety studies in non-human primates.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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