For research use only
| Cat No. | ABC-X0420C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Dog |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
CHOK1 cells stably expressing dog MUC1, ideal for veterinary cancer models, cross-species antibody testing, and mucin-targeted therapy research.
Xpress™ Dog MUC1 CHOK1 Overexpression Cell Line is a genetically engineered model derived from the parental Chinese hamster ovary (CHOK1) cell line based on customers’ requirements. The overexpression cell line is generated by stable integration of exogenous full-length dog MUC1 gene into CHOK1 host cells using our optimized lentiviral vector transduction system. Overexpression clone is validated at gene level by qRT-PCR.
Target
MUC1 (Mucin 1) encodes a transmembrane glycoprotein forming protective mucous barriers on epithelial surfaces. In dogs, MUC1 functions similarly and is implicated in epithelial biology and tumorigenesis, particularly in veterinary oncology. Aberrant MUC1 expression contributes to immune evasion and cancer progression. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Dog |
| Cat.No | ABC-X0420C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This Dog MUC1 CHOK1 Overexpression Cell Line serves as a vital tool for investigating MUC1-mediated mechanisms in canine epithelial cells and tumor progression. It is valuable for preclinical evaluation of MUC1-targeted immunotherapies and antibody development in comparative oncology.