Xpress™ Dog MUC1 Over-expressing Cell Line (CHOK1)

Description

Xpress™ Dog MUC1 CHOK1 Overexpression Cell Line is a genetically engineered model derived from the parental Chinese hamster ovary (CHOK1) cell line based on customers’ requirements. The overexpression cell line is generated by stable integration of exogenous full-length dog MUC1 gene into CHOK1 host cells using our optimized lentiviral vector transduction system. Overexpression clone is validated at gene level by qRT-PCR.
Target
MUC1 (Mucin 1) encodes a transmembrane glycoprotein forming protective mucous barriers on epithelial surfaces. In dogs, MUC1 functions similarly and is implicated in epithelial biology and tumorigenesis, particularly in veterinary oncology. Aberrant MUC1 expression contributes to immune evasion and cancer progression. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.