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Xpress™ Human ARV7 Over-expressing Cell Line (LNCap)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human ARV7 Over-expressing Cell Line (LNCap)
Species

Human
Cat.No

ABC-X0249C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Prostate
Disease

Carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

LNCap

Description

ARV7 LNCap Overexpression Cell Line is derived from androgen-responsive human prostate cancer LNCap cells. Stable ARV7 expression is achieved via lentiviral integration and validated by qRT-PCR. Cells are passaged below P20.
Target
ARV7 is a constitutively active androgen receptor splice variant, pivotal in castration-resistant prostate cancer and associated with treatment failure to enzalutamide or abiraterone. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This overexpression model facilitates investigation of ARV7 in androgen signaling and resistance mechanisms, and is applicable for testing ARV7-targeted therapeutics.

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