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Transfected Stable Cell Lines

Xpress™ Human ARV7 Over-expressing Cell Line (LNCap)

  • For research use only

Cat No.

ABC-X0249C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

LNCap
Source Organ

Prostate
Disease

Carcinoma
Storage

Liquid Nitrogen

The Xpress™ Human ARV7 over-expressing cell line (LNCap) serve as a prostate cancer model to explore resistance mechanisms to hormone therapy.

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  • Xpress™ Human ARV7 Over-expressing Cell Line (LNCap)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human ARV7 Over-expressing Cell Line (LNCap)

Description

ARV7 LNCap Overexpression Cell Line is derived from androgen-responsive human prostate cancer LNCap cells. Stable ARV7 expression is achieved via lentiviral integration and validated by qRT-PCR. Cells are passaged below P20.
Target
ARV7 is a constitutively active androgen receptor splice variant, pivotal in castration-resistant prostate cancer and associated with treatment failure to enzalutamide or abiraterone. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0249C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Prostate
Disease

Carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

LNCap
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This overexpression model facilitates investigation of ARV7 in androgen signaling and resistance mechanisms, and is applicable for testing ARV7-targeted therapeutics.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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