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Xpress™ Human CCR2a Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human CCR2a Over-expressing Cell Line (293T)
Species

Human
Cat.No

ABC-X0274C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

Xpress™ Human CCR2a Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (293T) parental cell line based on customers’ requirement. CCR2a 293T overexpression cell line is generated by stable integration of exogenous human CCR2a into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The CCR2a gene encodes a chemokine receptor variant involved in monocyte and macrophage recruitment to inflammatory sites. It binds CCL2 and other chemokines, mediating immune responses and contributing to diseases such as multiple sclerosis and cancer. The protein resides in the plasma membrane and activates G protein-dependent signaling cascades. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The CCR2a 293T Overexpression Cell Line serves as a powerful tool to investigate CCR2a-mediated chemokine signaling and leukocyte trafficking. This model supports drug discovery targeting chronic inflammation and tumor microenvironment modulation. It is utilized for evaluating antagonists and therapeutic antibodies against CCR2a.

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