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Xpress™ Human CD30 Over-expressing Cell Line (HT1080)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human CD30 Over-expressing Cell Line (HT1080)
Species

Human
Cat.No

ABC-X0121C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Connective Tissue
Disease

Fibrosarcoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

HT1080

Description

Xpress™ Human CD30 over-expressing cell line (HT1080) is a genetically engineered model developed from the human fibrosarcoma HT1080 cell line, tailored to express high levels of human CD30. Lentiviral vector-mediated transduction was employed to achieve stable gene integration and consistent expression.
Target
CD30 (TNFRSF8) is a member of the tumor necrosis factor receptor superfamily and is highly expressed in certain lymphomas, including Hodgkin’s lymphoma and anaplastic large cell lymphoma. It plays a role in T-cell activation and has emerged as a therapeutic target for antibody-drug conjugates and other immunotherapies.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Human CD30 over-expressing cell line (HT1080) serves as a research model for CD30-targeted therapeutic development, including antibody screening, cytotoxicity assays, and signal transduction studies in tumor immunology.

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