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Species | Human |
Cat.No | ABC-X0121C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Epithelial |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO₂ |
Source Organ | Connective Tissue |
Disease | Fibrosarcoma |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | HT1080 |
Xpress™ Human CD30 over-expressing cell line (HT1080) is a genetically engineered model developed from the human fibrosarcoma HT1080 cell line, tailored to express high levels of human CD30. Lentiviral vector-mediated transduction was employed to achieve stable gene integration and consistent expression.
Target
CD30 (TNFRSF8) is a member of the tumor necrosis factor receptor superfamily and is highly expressed in certain lymphomas, including Hodgkin’s lymphoma and anaplastic large cell lymphoma. It plays a role in T-cell activation and has emerged as a therapeutic target for antibody-drug conjugates and other immunotherapies.
For research use only