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Xpress™ Human CLDN1 Over-expressing Cell Line (CT26)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human CLDN1 Over-expressing Cell Line (CT26)
Species

Human
Cat.No

ABC-X0411C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Colon
Disease

Colorectal Carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CT26

Description

Human CLDN1 CT26 Overexpression Cell Line is a genetically engineered model derived from selected murine colon carcinoma (CT26) parental cell line based on customers’ requirement. Human CLDN1 CT26 overexpression cell line is generated by stable integration of exogenous human CLDN1 into CT26 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
CLDN1 is a tight junction protein that regulates paracellular permeability and epithelial integrity. It is frequently dysregulated in cancers, particularly colorectal, liver, and breast cancers, and contributes to tumor progression and metastasis.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model facilitates the study of human CLDN1’s oncogenic role in mouse tumor microenvironments, supports development of tight junction-targeted therapies, and enables evaluation of epithelial barrier modulation in colon cancer research.

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