For research use only
| Cat No. | ABC-X0395C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Lymphocytes |
| Species | Human |
| Host Cell | BAF3 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Stable BAF3 cell line overexpressing human cMET receptor, ideal for cancer pathway, RTK signaling, and targeted drug screening research applications.
Human cMET BAF3 Overexpression Cell Line is a genetically engineered model derived from selected murine pro-B cell (BAF3) parental cell line based on customers’ requirement. Human cMET BAF3 overexpression cell line is generated by stable integration of exogenous human cMET (MET) into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
cMET (MET), also known as hepatocyte growth factor receptor (HGFR), is a receptor tyrosine kinase implicated in a wide range of cellular processes including proliferation, survival, motility, and morphogenesis. Aberrant cMET signaling is associated with the development and progression of various human cancers, making it a key therapeutic target.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0395C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphocytes |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | BAF3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This overexpression cell line provides a reliable in vitro model for studying the role of human cMET in signal transduction, tumorigenesis, and drug resistance. It can be applied in target validation, functional analysis, and anti-cancer drug screening. Its stable and consistent expression profile makes it particularly suitable for high-throughput assays and mechanistic research into the cMET pathway.