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Xpress™ Human DDR2 Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human DDR2 Over-expressing Cell Line (293T)
Species

Human
Cat.No

ABC-X0038C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

Xpress™ Human DDR2 Over-expressing Cell Line (293T) is a genetically engineered model derived from HEK293T parental cells based on customers’ requirement. This overexpression cell line is developed by stable integration of exogenous human DDR2 gene into the 293T host cells using our optimized lentiviral transduction system.
Target
DDR2 (Discoidin Domain Receptor 2) is a receptor tyrosine kinase that binds to collagen and mediates extracellular matrix remodeling, cell adhesion, and epithelial-to-mesenchymal transition (EMT). Its overexpression and activation are implicated in tumor progression, fibrosis, and metastasis, particularly in squamous cell lung carcinoma and breast cancer. AcceGen offers stable overexpression models for a wide range of genes involved in cancer biology and regenerative medicine. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Human DDR2 Over-expressing Cell Line (293T) serves as a robust tool for studying DDR2-driven signaling cascades, drug response profiling, and fibrotic disease modeling. It is also suitable for high-throughput screening of DDR2-targeted therapeutics and mechanistic studies of tumor-stroma interactions.

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