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Transfected Stable Cell Lines

Xpress™ Human EGFRvA Over-expressing Cell Line (BAF3)

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Species

Human

Cat.No

ABC-X0334C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocytes

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Description

Xpress™ Human EGFRvA Overexpression Cell Line is a genetically engineered model derived from selected murine pro-B (BAF3) parental cell line based on customers’ requirement. EGFRvA BAF3 overexpression cell line is generated by stable integration of exogenous human EGFRvA into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The EGFRvA variant is a modified form of the epidermal growth factor receptor, frequently associated with aberrant signaling in cancers. EGFR family members regulate proliferation, survival, and differentiation. Mutated variants like EGFRvA drive oncogenic signaling in lung and brain tumors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The EGFRvA BAF3 Overexpression Cell Line serves as a powerful model to investigate aberrant EGFR signaling in oncogenesis. This system supports the development and testing of targeted EGFR inhibitors in precision oncology.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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