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Transfected Stable Cell Lines

Xpress™ Human EGFRvA Over-expressing Cell Line (BAF3)

  • For research use only

Cat No.

ABC-X0334C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

BAF3 cells stably overexpressing human EGFRvA mutant, suitable for research on constitutive signaling, tumorigenesis, and targeted cancer therapy testing.

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  • Xpress™ Human EGFRvA Over-expressing Cell Line (BAF3)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human EGFRvA Over-expressing Cell Line (BAF3)

Description

Xpress™ Human EGFRvA Overexpression Cell Line is a genetically engineered model derived from selected murine pro-B (BAF3) parental cell line based on customers’ requirement. EGFRvA BAF3 overexpression cell line is generated by stable integration of exogenous human EGFRvA into BAF3 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The EGFRvA variant is a modified form of the epidermal growth factor receptor, frequently associated with aberrant signaling in cancers. EGFR family members regulate proliferation, survival, and differentiation. Mutated variants like EGFRvA drive oncogenic signaling in lung and brain tumors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0334C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The EGFRvA BAF3 Overexpression Cell Line serves as a powerful model to investigate aberrant EGFR signaling in oncogenesis. This system supports the development and testing of targeted EGFR inhibitors in precision oncology.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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