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Transfected Stable Cell Lines

Xpress™ Human EP4 Over-expressing Cell Line (HEK293)

  • For research use only

Cat No.

ABC-X0147C
Product Type

Overexpression Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

HEK293
Source Organ

Kidney
Disease

Normal
Storage

Liquid Nitrogen

The Xpress™ EP4 HEK293 cell line offers a robust model for studying PGE2 signaling and GPCR pathways. Ideal for cancer research and drug screening.

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  • Xpress™ Human EP4 Over-expressing Cell Line (HEK293)
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human EP4 Over-expressing Cell Line (HEK293)

Description

Xpress™ Human EP4 over-expressing cell line (HEK293) is a genetically engineered model derived from selected human embryonic kidney HEK293 parental cell line based on customers’ requirement. EP4 HEK293 overexpression cell line is generated by stable integration of exogenous human EP4 (PTGER4) into HEK293 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The EP4 receptor, encoded by PTGER4, is a G-protein-coupled receptor for prostaglandin E2 (PGE2), involved in inflammation, angiogenesis, and tumor progression. EP4 overexpression is linked to immunosuppression and metastasis in breast and colorectal cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0147C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

HEK293
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The EP4 HEK293 Overexpression Cell Line is suited for screening of EP4 antagonists, understanding PGE2 signaling in inflammation and cancer, and assessing GPCR-related pathway modulation.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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