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Xpress™ Human ERBB4 Over-expressing Cell Line (BAF3)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human ERBB4 Over-expressing Cell Line (BAF3)
Species

Human
Cat.No

ABC-X0010C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Xpress™ Human ERBB4 over-expressing cell line (BAF3) is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. Xpress™ ERBB4 BAF3 overexpression cell line is generated by stable integration of exogenous human ERBB4 into Ba/F3 host cells using our optimized transduction of lentiviral vectors.
Target
ERBB4 (HER4) is a receptor tyrosine kinase of the EGFR family and participates in cellular processes including proliferation, differentiation, and survival. Upon ligand binding, ERBB4 undergoes dimerization and activates downstream signaling cascades such as PI3K/AKT and MAPK/ERK. Overexpression of ERBB4 has been linked to neurodevelopmental disorders and certain cancers, where it may promote or suppress tumorigenesis depending on the isoform and cellular context. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ ERBB4 Over-expressing Cell Line (BAF3) serves as a powerful tool to investigate ERBB4 signaling dynamics and receptor-targeted therapeutic strategies. This model enables functional studies of receptor activation, IL-3-independent growth, and drug sensitivity. It is utilized for high-throughput screening of ERBB4-targeted small molecules, antibody-based agents, and pathway modulators.

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