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Transfected Stable Cell Lines

Xpress™ Human FZD10 Over-expressing Cell Line (CHOK1)

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Species

Human

Cat.No

ABC-X0169C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Ovary

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

CHOK1

Description

FZD10 CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. FZD10 CHOK1 overexpression cell line is generated by stable integration of exogenous human FZD10 into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The FZD10 gene encodes a seven-transmembrane domain protein of the Frizzled family that functions as a receptor in the Wnt signaling pathway. FZD10 overexpression is implicated in the progression of synovial sarcoma, colorectal cancer, and gastric cancer, where it promotes tumor proliferation, migration, and resistance to apoptosis. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The FZD10 CHOK1 Overexpression Cell Line serves as a valuable model for investigating Wnt/β-catenin signaling activation and downstream oncogenic transcription. It is suitable for drug screening targeting Wnt pathway receptors and elucidating tumor cell survival mechanisms.

Inquiring Xpress™ Human FZD10 Over-expressing Cell Line (CHOK1)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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