For research use only
| Cat No. | ABC-X0146C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The ICOSLG CHOK1 cell line offers a stable model for investigating T-cell interactions and tumor microenvironments. Perfect for your research needs!
Xpress™ Human ICOSLG over-expressing cell line (CHOK1) is a genetically engineered model derived from selected Chinese hamster ovary CHOK1 parental cell line based on customers’ requirement. ICOSLG CHOK1 overexpression cell line is generated by stable integration of exogenous human ICOSLG (CD275) into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The ICOSLG gene encodes the ligand for inducible T-cell co-stimulator (ICOS), a key regulator of T-cell activation and immune response. ICOSLG is involved in tumor immune evasion and is overexpressed in several cancers, contributing to immunosuppressive tumor microenvironments. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0146C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The ICOSLG CHOK1 Overexpression Cell Line is an effective model to study T-cell co-stimulation and tumor immunology. It is widely used for functional screening of ICOS–ICOSLG interactions and development of ICOS-targeted immunotherapies.