Transfected Stable Cell Lines

Xpress™ Human IGF1R Over-expressing Cell Line (CHOK1)

  • For research use only

Cat No.

ABC-X0367C

Product Type

Overexpression Stable Cell Lines

Cell Type

Epithelial

Species

Human

Host Cell

CHOK1

Source Organ

Ovary

Disease

Normal

Storage

Liquid Nitrogen

Human IGF1R stably expressed in CHOK1 cells, widely used in cancer proliferation, insulin-like growth signaling, and therapeutic target validation research.

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Description

IGF1R CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. IGF1R CHOK1 overexpression cell line is generated by stable integration of exogenous human IGF1R into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The IGF1R gene encodes the insulin-like growth factor 1 receptor, a transmembrane tyrosine kinase receptor involved in cell growth, survival, and metabolism. IGF1R is overexpressed in a variety of cancers and contributes to tumorigenesis, resistance to therapy, and metastatic progression. It represents a target for anticancer therapeutics including monoclonal antibodies and small molecule inhibitors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0367C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Ovary

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

CHOK1

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The IGF1R CHOK1 Overexpression Cell Line serves as a powerful tool to investigate IGF1R signaling pathways and therapeutic blockade. This model enables studies on proliferation, anti-apoptotic mechanisms, and resistance to targeted therapies. It is used for high-throughput screening of IGF1R inhibitors and monoclonal antibodies in oncology drug development.

Inquiring Xpress™ Human IGF1R Over-expressing Cell Line (CHOK1)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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