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Xpress™ Human IGF1R Over-expressing Cell Line (CHOK1)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human IGF1R Over-expressing Cell Line (CHOK1)
Species

Human
Cat.No

ABC-X0367C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

IGF1R CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. IGF1R CHOK1 overexpression cell line is generated by stable integration of exogenous human IGF1R into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The IGF1R gene encodes the insulin-like growth factor 1 receptor, a transmembrane tyrosine kinase receptor involved in cell growth, survival, and metabolism. IGF1R is overexpressed in a variety of cancers and contributes to tumorigenesis, resistance to therapy, and metastatic progression. It represents a target for anticancer therapeutics including monoclonal antibodies and small molecule inhibitors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The IGF1R CHOK1 Overexpression Cell Line serves as a powerful tool to investigate IGF1R signaling pathways and therapeutic blockade. This model enables studies on proliferation, anti-apoptotic mechanisms, and resistance to targeted therapies. It is used for high-throughput screening of IGF1R inhibitors and monoclonal antibodies in oncology drug development.

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