For research use only
| Cat No. | ABC-X0367C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Human |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human IGF1R stably expressed in CHOK1 cells, widely used in cancer proliferation, insulin-like growth signaling, and therapeutic target validation research.
IGF1R CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. IGF1R CHOK1 overexpression cell line is generated by stable integration of exogenous human IGF1R into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The IGF1R gene encodes the insulin-like growth factor 1 receptor, a transmembrane tyrosine kinase receptor involved in cell growth, survival, and metabolism. IGF1R is overexpressed in a variety of cancers and contributes to tumorigenesis, resistance to therapy, and metastatic progression. It represents a target for anticancer therapeutics including monoclonal antibodies and small molecule inhibitors. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0367C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The IGF1R CHOK1 Overexpression Cell Line serves as a powerful tool to investigate IGF1R signaling pathways and therapeutic blockade. This model enables studies on proliferation, anti-apoptotic mechanisms, and resistance to targeted therapies. It is used for high-throughput screening of IGF1R inhibitors and monoclonal antibodies in oncology drug development.