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Transfected Stable Cell Lines

Xpress™ Human IL2RB Over-expressing Cell Line (CHOK1)

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Species

Human

Cat.No

ABC-X0372C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Ovary

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

CHOK1

Description

IL2RB CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. IL2RB CHOK1 overexpression cell line is generated by stable integration of exogenous human IL2RB into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The IL2RB gene encodes the beta subunit of the interleukin-2 receptor, which is essential for high-affinity IL-2 signaling in T cells and NK cells. IL2RB forms a complex with IL2RA and IL2RG to mediate immune activation, proliferation, and survival. Dysregulation of IL2RB expression and function has been implicated in immune disorders and cancer immunotherapy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The IL2RB CHOK1 Overexpression Cell Line serves as a powerful tool to investigate IL-2 receptor signaling and cytokine-driven immune responses. This model enables mechanistic studies of receptor-ligand binding, downstream STAT signaling, and therapeutic modulation. It is widely used in screening IL2/IL2R-targeted biologics and understanding T/NK cell activation dynamics.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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