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Transfected Stable Cell Lines

Xpress™ Human LOXL4 Over-expressing Cell Line (293T)

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Species

Human

Cat.No

ABC-X0202C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Kidney

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

293T

Description

The LOXL4 293T Overexpression Cell Line is a genetically engineered model derived from human embryonic kidney 293T cells based on customers’ requirement. LOXL4 293T overexpression cell line is generated by stable integration of exogenous human LOXL4 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The LOXL4 gene encodes lysyl oxidase-like 4, an enzyme involved in extracellular matrix remodeling and crosslinking of collagen and elastin. LOXL4 is implicated in tumor progression, metastasis, and hypoxia-induced signaling in various cancers, including hepatocellular carcinoma and breast cancer. Its dysregulation correlates with fibrotic disease and poor clinical prognosis. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The LOXL4 293T Overexpression Cell Line serves as a valuable tool to investigate LOXL4-mediated ECM remodeling, metastatic potential, and tumor microenvironment modulation. It supports drug screening targeting hypoxia-related fibrotic and neoplastic processes.

Inquiring Xpress™ Human LOXL4 Over-expressing Cell Line (293T)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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