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Xpress™ Human LOXL4 Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human LOXL4 Over-expressing Cell Line (293T)
Species

Human
Cat.No

ABC-X0202C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

The LOXL4 293T Overexpression Cell Line is a genetically engineered model derived from human embryonic kidney 293T cells based on customers’ requirement. LOXL4 293T overexpression cell line is generated by stable integration of exogenous human LOXL4 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The LOXL4 gene encodes lysyl oxidase-like 4, an enzyme involved in extracellular matrix remodeling and crosslinking of collagen and elastin. LOXL4 is implicated in tumor progression, metastasis, and hypoxia-induced signaling in various cancers, including hepatocellular carcinoma and breast cancer. Its dysregulation correlates with fibrotic disease and poor clinical prognosis. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The LOXL4 293T Overexpression Cell Line serves as a valuable tool to investigate LOXL4-mediated ECM remodeling, metastatic potential, and tumor microenvironment modulation. It supports drug screening targeting hypoxia-related fibrotic and neoplastic processes.

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