For research use only
| Cat No. | ABC-X0263C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial-like |
| Species | Human |
| Host Cell | B16F10 |
| Source Organ | Skin |
| Disease | Melanoma |
| Storage | Liquid Nitrogen |
Xpress™ Human LY6K over-expressing B16F10 cells provide a valuable melanoma model for investigating cancer-testis antigen expression and function.
This cell model is established by transducing B16F10 murine melanoma cells with lentivirus encoding human LY6K gene. Clones are maintained below passage 20 and verified by qRT-PCR.
Target
LY6K is a cancer-testis antigen involved in tumor growth, immune escape, and chemoresistance, and is highly expressed in several malignancies including breast and bladder cancer. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0263C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Skin |
| Disease | Melanoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | B16F10 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
LY6K B16F10 overexpression cell line is valuable for investigating tumor immunogenicity, evaluating cancer vaccines, and screening LY6K-targeted therapies in melanoma and other tumors.