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Xpress™ Human MMP7 Over-expressing Cell Line (MC38)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human MMP7 Over-expressing Cell Line (MC38)
Species

Human
Cat.No

ABC-X0144C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Colon
Disease

Colon Adenocarcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

MC38

Description

Xpress™ Human MMP7 over-expressing cell line (MC38) is a genetically engineered model derived from selected murine colon adenocarcinoma MC38 parental cell line based on customers’ requirement. MMP7 MC38 overexpression cell line is generated by stable integration of exogenous human MMP7 into MC38 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The MMP7 gene encodes matrix metallopeptidase 7, a zinc-dependent protease that degrades components of the extracellular matrix and is crucial for tissue remodeling, inflammation, and cancer metastasis. MMP7 is overexpressed in colorectal, pancreatic, and lung cancers, where it facilitates invasion, angiogenesis, and tumor growth via ECM breakdown and signaling molecule activation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The MMP7 MC38 Overexpression Cell Line offers a syngeneic-compatible platform for studying matrix remodeling and immune-tumor interactions in murine models. It is valuable for mechanistic analysis and in vivo drug efficacy testing of MMP7-targeted therapies.

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