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Species | Human |
Cat.No | ABC-X0435C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Epithelial |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO2 |
Source Organ | Kidney |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | 293T |
Xpress™ Human NOGGIN 293T Overexpression Cell Line is a genetically engineered model derived from HEK293T parental cells based on customers’ requirements. The overexpression cell line is generated by stable lentiviral transduction of the full-length human NOGGIN gene into 293T host cells. Overexpression clone is validated at gene level by qRT-PCR.
Target
Noggin is a secreted antagonist of bone morphogenetic proteins (BMPs) and plays an essential role in embryonic development, neural patterning, and bone formation. It modulates the BMP signaling pathway, which is involved in various developmental disorders and cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
Application
The Human NOGGIN 293T Overexpression Cell Line provides a reliable system for studying BMP signaling regulation and for screening compounds affecting developmental and bone-related pathways.
For research use only