+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Xpress™ Human PD1 Over-expressing Cell Line (H22)

  • For research use only

Cat No.

ABC-X0314C
Product Type

Overexpression Stable Cell Lines
Cell Type

Hepatoma Cell
Species

Human
Host Cell

H22
Source Organ

Liver
Disease

Hepatocellular carcinoma
Storage

Liquid Nitrogen

Human PD-1 stably expressed in H22 cells, designed for immune checkpoint inhibition assays, T cell dysfunction analysis, and immunotherapy research use.

Product Image
  • Xpress™ Human PD1 Over-expressing Cell Line (H22)
Get a Quote
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human PD1 Over-expressing Cell Line (H22)

Description

Xpress™ Human PD1 Overexpression Cell Line is a genetically engineered model derived from selected murine hepatoma (H22) parental cell line based on customers’ requirement. PD1 H22 overexpression cell line is generated by stable integration of exogenous human PD1 into H22 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The PD1 gene encodes a key immune checkpoint receptor expressed on activated T cells, regulating immune tolerance and preventing autoimmunity. It binds PD-L1 and PD-L2, leading to T cell exhaustion. PD1 is a crucial target in cancer immunotherapy, particularly in solid tumors and lymphomas. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0314C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Hepatoma Cell
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Liver
Disease

Hepatocellular carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

H22
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The PD1 H22 Overexpression Cell Line serves as a powerful tool for studying PD1 signaling and immune checkpoint blockade. It is widely used in immuno-oncology for evaluating anti-PD1 monoclonal antibodies and exploring immune evasion mechanisms.

  • Online Inquiry
  • Product Reviews

Inquiring Xpress™ Human PD1 Over-expressing Cell Line (H22)

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button