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Xpress™ Human PD1 Over-expressing Cell Line (H22)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human PD1 Over-expressing Cell Line (H22)
Species

Human
Cat.No

ABC-X0314C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Hepatoma Cell
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Liver
Disease

Hepatocellular carcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

H22

Description

Xpress™ Human PD1 Overexpression Cell Line is a genetically engineered model derived from selected murine hepatoma (H22) parental cell line based on customers’ requirement. PD1 H22 overexpression cell line is generated by stable integration of exogenous human PD1 into H22 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The PD1 gene encodes a key immune checkpoint receptor expressed on activated T cells, regulating immune tolerance and preventing autoimmunity. It binds PD-L1 and PD-L2, leading to T cell exhaustion. PD1 is a crucial target in cancer immunotherapy, particularly in solid tumors and lymphomas. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The PD1 H22 Overexpression Cell Line serves as a powerful tool for studying PD1 signaling and immune checkpoint blockade. It is widely used in immuno-oncology for evaluating anti-PD1 monoclonal antibodies and exploring immune evasion mechanisms.

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