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Species | Human |
Cat.No | ABC-X0135C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Epithelial |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO₂ |
Source Organ | Ovary |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | CHOK1 |
Xpress™ Human PDL1 over-expressing cell line is a genetically engineered model derived from selected CHOK1 parental cell line based on customers’ requirement. Human PDL1 overexpression cell line is generated by stable integration of exogenous human PDL1 (CD274) into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
PDL1 (Programmed death-ligand 1) is an immune checkpoint ligand that binds PD-1 to inhibit T cell responses. Its overexpression allows tumors to escape immune surveillance. PDL1 is widely studied in cancer immunotherapy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
For research use only