1
Discover top-quality products tailored for scientific and medical research. Request a personalized quote today
to enhance your projects.
| Species | Human |
| Cat.No | ABC-X0141C |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Skin |
| Disease | Melanoma |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | B16/F10 |
Xpress™ Human PVRL4 over-expressing cell line (B16/F10) is a genetically engineered model derived from selected murine B16/F10 parental cell line. Human PVRL4 overexpression cell line is generated by stable integration of exogenous human PVRL4 gene into B16/F10 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
PVRL4 (Nectin-4) is a cell adhesion molecule involved in epithelial tissue integrity and tumor progression. It is overexpressed in various cancers, including breast, bladder, and lung cancers, and serves as a target for antibody-drug conjugates such as enfortumab vedotin.
For research use only