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Xpress™ Human PVRL4 Over-expressing Cell Line (CHOK1)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human PVRL4 Over-expressing Cell Line (CHOK1)
Species

Human
Cat.No

ABC-X0129C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

Xpress™ Human PVRL4 over-expressing cell line (CHOK1) is a CHOK1-based model engineered to stably express the human PVRL4 gene, also known as nectin-4, using lentiviral gene delivery for consistent and robust surface presentation.
Target
PVRL4 (Nectin-4) is a cell adhesion molecule overexpressed in multiple cancers, including breast, bladder, and lung cancers. It has been identified as a tumor-associated antigen and is the target of the FDA-approved antibody-drug conjugate enfortumab vedotin.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Human PVRL4 over-expressing cell line (CHOK1) is an ideal system for tumor antigen validation, antibody binding and cytotoxicity assays, and evaluation of PVRL4-targeted therapeutics in oncology research.

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High Viability
To succeed in cell culture
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To support a consistent result
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