Transfected Stable Cell Lines

Xpress™ Human PVRL4 Over-expressing Cell Line (CHOK1)

  • For research use only

Cat No.

ABC-X0129C

Product Type

Overexpression Stable Cell Lines

Cell Type

Epithelial

Species

Human

Host Cell

CHOK1

Source Organ

Ovary

Disease

Normal

Storage

Liquid Nitrogen

The Human PVRL4 Overexpression Cell Line (CHOK1) provides an ideal platform for tumor antigen validation and targeted therapy, aiding cancer research.

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Description

Xpress™ Human PVRL4 over-expressing cell line (CHOK1) is a CHOK1-based model engineered to stably express the human PVRL4 gene, also known as nectin-4, using lentiviral gene delivery for consistent and robust surface presentation.
Target
PVRL4 (Nectin-4) is a cell adhesion molecule overexpressed in multiple cancers, including breast, bladder, and lung cancers. It has been identified as a tumor-associated antigen and is the target of the FDA-approved antibody-drug conjugate enfortumab vedotin.

Species

Human

Cat.No

ABC-X0129C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Epithelial

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO₂

Source Organ

Ovary

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

CHOK1

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Xpress™ Human PVRL4 over-expressing cell line (CHOK1) is an ideal system for tumor antigen validation, antibody binding and cytotoxicity assays, and evaluation of PVRL4-targeted therapeutics in oncology research.

Inquiring Xpress™ Human PVRL4 Over-expressing Cell Line (CHOK1)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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