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Transfected Stable Cell Lines

Xpress™ Human RANKL Over-expressing Cell Line (CHOK1)

  • BSL

    1

  • 40
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human RANKL Over-expressing Cell Line (CHOK1)
Species

Human
Cat.No

ABC-X0241C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

This model was generated by integrating full-length human RANKL into the CHOK1 genome via lentiviral vectors. Stable expression was confirmed by qRT-PCR.
Target
RANKL (Receptor Activator of Nuclear Factor κB Ligand) is a key regulator of osteoclast differentiation and immune modulation. It is a therapeutic target in osteoporosis, rheumatoid arthritis, and cancer-induced bone disease. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model is used for mechanistic studies of bone resorption, osteoimmunology, and development of anti-RANKL therapies such as denosumab.

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