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Xpress™ Human SCN11A Over-expressing Cell Line (HEK293)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human SCN11A Over-expressing Cell Line (HEK293)
Species

Human
Cat.No

ABC-X0170C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

HEK293

Description

SCN11A HEK293 Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (HEK293) parental cell line based on customers’ requirement. SCN11A HEK293 overexpression cell line is generated by stable integration of exogenous human SCN11A into HEK293 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The SCN11A gene encodes the Nav1.9 voltage-gated sodium channel, predominantly expressed in peripheral sensory neurons and associated with pain perception. Mutations and dysregulation of SCN11A are linked to familial episodic pain syndromes, congenital insensitivity to pain, and visceral hypersensitivity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The SCN11A HEK293 Overexpression Cell Line provides a useful platform for studying ion channel function, nociceptive signal transduction, and screening of Nav1.9-specific blockers or modulators for neuropathic pain treatment.

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