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Species | Human |
Cat.No | ABC-X0127C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Epithelial |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO₂ |
Source Organ | Ovary |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | CHOK1 |
Xpress™ Human SIGLEC14 over-expressing cell line (CHOK1) is a CHOK1-derived cell line genetically engineered to stably express human SIGLEC14 through lentiviral vector transduction. The model ensures high surface expression suitable for glycoimmunology research.
Target
SIGLEC14 is a sialic acid-binding immunoglobulin-like lectin expressed on innate immune cells such as monocytes and neutrophils. It promotes pro-inflammatory responses and is implicated in host defense, inflammation, and respiratory diseases. Genetic variations in SIGLEC14 are associated with differential immune responses in humans.
For research use only