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Xpress™ Human TPBG Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Human TPBG Over-expressing Cell Line (293T)
Species

Human
Cat.No

ABC-X0250C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

TPBG 293T Overexpression Cell Line is created from human embryonic kidney 293T cells with stable lentiviral integration of TPBG. Overexpression is validated by qRT-PCR, with cells cultured at <P20 passages. Target TPBG (Trophoblast glycoprotein), also known as 5T4, is a transmembrane protein implicated in tumor progression, epithelial-mesenchymal transition, and immune evasion. It is upregulated in various cancers including colorectal and ovarian. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model enables mechanistic studies and drug screening for anti-TPBG therapeutics and CAR-T strategies targeting 5T4-expressing tumors.

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