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Xpress™ Mouse B7H3 Over-expressing Cell Line (CHOK1)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse B7H3 Over-expressing Cell Line (CHOK1)
Species

Mouse
Cat.No

ABC-X0424C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

Xpress™ Mouse B7H3 CHOK1 Overexpression Cell Line is a genetically engineered model derived from the Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirements. The overexpression cell line is generated by stable lentiviral-mediated integration of the full-length mouse B7H3 gene into CHOK1 host cells. Overexpression clone is validated at gene level by qRT-PCR.
Target
B7H3 (CD276) is an immunoregulatory transmembrane protein involved in modulation of T cell responses. Mouse B7H3 is implicated in tumor immune evasion and is overexpressed in various cancers, correlating with poor prognosis. It is a promising target for cancer immunotherapy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This Mouse B7H3 CHOK1 Overexpression Cell Line is used to study immune checkpoint pathways and tumor microenvironment interactions. It facilitates screening of B7H3-targeted antibodies and evaluation of novel immunotherapeutic strategies.

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