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Xpress™ Mouse FGFR3IIIC Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse FGFR3IIIC Over-expressing Cell Line (293T)
Species

Mouse
Cat.No

ABC-X0111C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

Xpress™ Mouse FGFR3IIIC over-expressing cell line (293T) is a genetically engineered model derived from selected 293T parental cell line based on customers’ requirement. Mouse FGFR3IIIC overexpression cell line is generated by stable integration of exogenous mouse FGFR3IIIC splice variant into 293T host cells using our optimized transduction of lentiviral vectors.
Target
FGFR3IIIC is an alternatively spliced isoform of fibroblast growth factor receptor 3 that alters ligand binding specificity and plays distinct roles in development and tumorigenesis. It is involved in bone growth regulation, cell differentiation, and cancer progression. AcceGen offers isoform-specific overexpression models to dissect alternative splicing functions. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Mouse FGFR3IIIC over-expressing cell line (293T) serves as a useful tool to explore FGFR3 isoform-specific functions and screen FGFR inhibitors. It facilitates studies on bone disorders, cancer biology, and FGF signaling.

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