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Xpress™ Mouse GPC3 Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse GPC3 Over-expressing Cell Line (293T)
Species

Mouse
Cat.No

ABC-X0418C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

Mouse GPC3 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (293T) parental cell line based on customers’ requirement. Mouse GPC3 293T overexpression cell line is generated by stable integration of exogenous mouse GPC3 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
GPC3 regulates cell growth and differentiation through interaction with Wnt and Hedgehog signaling pathways. Its overexpression is observed in liver tumors and developmental abnormalities.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model facilitates research on species-specific GPC3 signaling and enables comparative validation of immunotherapies targeting GPC3 in murine and human contexts.

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