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Xpress™ Mouse MR1 Over-expressing Cell Line (MC38)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse MR1 Over-expressing Cell Line (MC38)
Species

Mouse
Cat.No

ABC-X0117C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial-like
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Colon
Disease

Colon Adenocarcinoma
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

MC38

Description

Xpress™ Mouse MR1 over-expressing cell line (MC38) is a genetically engineered model derived from selected murine MC38 parental cell line based on customers’ requirement. Mouse MR1 overexpression cell line is generated by stable integration of exogenous mouse MR1 gene into MC38 host cells using our optimized transduction of lentiviral vectors.
Target
MR1 (MHC class I-related molecule) is a non-classical MHC molecule that presents microbial metabolites to mucosal-associated invariant T (MAIT) cells. It plays an important role in innate-like T cell responses and antimicrobial immunity. AcceGen supports generation of immune modulation models in murine systems. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Xpress™ Mouse MR1 over-expressing cell line (MC38) is a valuable tool for studying MAIT cell biology and antigen presentation pathways. It enables preclinical immunological research in syngeneic mouse tumor models and supports MAIT-based therapeutic discovery.

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