For research use only
| Cat No. | ABC-X0383C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Mouse |
| Host Cell | CHOK1 |
| Source Organ | Ovary |
| Disease | Normal |
| Storage | Liquid Nitrogen |
CHOK1 cells engineered to overexpress mouse Muc1, ideal for mucin signaling, epithelial barrier studies, and cancer immunotherapy model development.
Muc1 CHOK1 Overexpression Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. Muc1 CHOK1 overexpression cell line is generated by stable integration of exogenous mouse Muc1 into CHOK1 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The Muc1 gene encodes a transmembrane mucin glycoprotein that contributes to epithelial protection, signaling, and adhesion. In cancer, Muc1 is overexpressed and aberrantly glycosylated, promoting oncogenesis, metastasis, and immune evasion. It plays roles in modulating inflammatory responses and is a target for immunotherapy. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Mouse |
| Cat.No | ABC-X0383C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Ovary |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | CHOK1 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Muc1 CHOK1 Overexpression Cell Line serves as a powerful tool to investigate mucin-related tumorigenesis, immune suppression, and drug resistance mechanisms. This model supports screening of Muc1-targeted therapies and studying mucin-driven signaling cascades in cancer biology.