For research use only
| Cat No. | ABC-X0377C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Mouse |
| Host Cell | 293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Mouse ROR2 stably expressed in 293T cells, applied in developmental signaling, non-canonical Wnt pathway research, and studies on tumor cell migration.
ROR2 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (293T) parental cell line based on customers’ requirement. ROR2 293T overexpression cell line is generated by stable integration of exogenous mouse ROR2 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The ROR2 gene encodes a receptor tyrosine kinase-like orphan receptor involved in Wnt5a signaling and embryonic development. In cancer, ROR2 regulates cell migration, invasion, and metastasis. Aberrant expression of ROR2 is observed in sarcomas and other malignancies, making it a potential therapeutic target. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Mouse |
| Cat.No | ABC-X0377C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | 293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The ROR2 293T Overexpression Cell Line serves as a powerful tool to investigate Wnt/ROR2 signaling in oncogenesis and tissue morphogenesis. This model enables studies of ROR2-mediated EMT and metastatic progression and is used for screening ROR2-targeted therapeutics.