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Xpress™ Mouse ROR2 Over-expressing Cell Line (293T)

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Xpress™ Mouse ROR2 Over-expressing Cell Line (293T)
Species

Mouse
Cat.No

ABC-X0377C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

ROR2 293T Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (293T) parental cell line based on customers’ requirement. ROR2 293T overexpression cell line is generated by stable integration of exogenous mouse ROR2 into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The ROR2 gene encodes a receptor tyrosine kinase-like orphan receptor involved in Wnt5a signaling and embryonic development. In cancer, ROR2 regulates cell migration, invasion, and metastasis. Aberrant expression of ROR2 is observed in sarcomas and other malignancies, making it a potential therapeutic target. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The ROR2 293T Overexpression Cell Line serves as a powerful tool to investigate Wnt/ROR2 signaling in oncogenesis and tissue morphogenesis. This model enables studies of ROR2-mediated EMT and metastatic progression and is used for screening ROR2-targeted therapeutics.

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