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Transfected Stable Cell Lines

Xpress™ Mouse TPBG Over-expressing Cell Line (293T)

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Species

Mouse

Cat.No

ABC-X0297C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Epithelial

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Kidney

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

293T

Description

Xpress™ Mouse TPBG Overexpression Cell Line is a genetically engineered model derived from selected human embryonic kidney (293T) parental cell line based on customers’ requirement. TPBG 293T overexpression cell line is generated by stable integration of exogenous mouse TPBG into 293T host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
The TPBG gene (trophoblast glycoprotein), also known as 5T4, encodes a membrane glycoprotein involved in cell adhesion and motility. It is upregulated in embryonic development and various cancers, including colorectal and gastric cancer, and is associated with tumor progression and metastasis. TPBG participates in Wnt/β-catenin signaling and modulates cell migration. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • The TPBG 293T Overexpression Cell Line serves as a powerful tool to investigate TPBG-mediated tumorigenesis, cell adhesion, and cancer immunotherapy. This model enables studies on TPBG-targeted antibody therapies and functional screening in cancer biology.

Inquiring Xpress™ Mouse TPBG Over-expressing Cell Line (293T)

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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