Induced Pluripotent Stem Cells (iPSCs)

Induced pluripotent stem cells (iPSCs) are somatic cells—typically skin fibroblasts or peripheral blood cells—that have been genetically reprogrammed into a pluripotent state. These cells exhibit key characteristics of embryonic stem cells, including unlimited self-renewal and the capacity to differentiate into nearly any cell type in the human body. iPSCs have revolutionized the fields of regenerative medicine, disease modeling, and drug discovery by providing a versatile, patient-specific, and ethically sound alternative to embryonic stem cells.

iPSCs enable the generation of patient-derived cellular models that faithfully preserve the genetic background of the individual. This allows researchers to study complex genetic disorders, track disease progression in vitro, and evaluate therapeutic efficacy in a controlled, individualized context. The ability to establish iPSC lines from individuals with specific genetic mutations has been transformative for investigating rare diseases and stratifying patient responses in drug development pipelines.

Functionally, iPSCs serve as the starting point for generating specialized human cell types—including neurons, cardiomyocytes, hepatocytes, and hematopoietic lineages—via directed differentiation protocols. Their applications span developmental biology, toxicology, preclinical drug screening, and regenerative tissue engineering.

To support innovation in this rapidly evolving field, AcceGen offers a curated collection of high-quality human and animal iPSC lines. Our iPSCs are rigorously validated for key pluripotency markers, genomic stability, and differentiation potential. Available in both healthy and disease-specific formats, AcceGen’s iPSCs offer reliability, reproducibility, and clinical relevance for advanced life science research.

Explore our iPSC catalog to discover the tools you need to advance your scientific goals.