For research use only
| Cat No. | ABC-RC038Y |
| Product Type | Reporter Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Mouse |
| Host Cell | 4T1 |
| Source Organ | Breast |
| Disease | Mouse breast cancer |
| Storage | Liquid Nitrogen |
4T1/RFP Luciferase HSV1-tk Stable Cell Line by AcceGen is for multimodal tumor tracking (RFP/FLuc) and ganciclovir-mediated ablation (suicide gene).
4T1/RFP Luciferase HSV1-tk Stable Cell Line is a triple-reporter system engineered from the highly metastatic murine 4T1 mammary carcinoma line, stably co-expressing red fluorescent protein (RFP), Luciferase, and truncated herpes simplex virus type 1 thymidine kinase (HSV1-tk). This unique combination enables multimodal tracking through fluorescence imaging (RFP), bioluminescence detection (Luc), and PET imaging. The cells retain parental 4T1 characteristics including epithelial morphology and aggressive metastatic potential while providing three independent quantitative readouts for tumor progression studies, drug screening, and therapeutic monitoring. Maintained at low passages (<P20) to ensure reporter stability, this cell line is particularly valuable for longitudinal cancer research requiring cross-validation between imaging modalities. The cells have undergone rigorous quality control testing and are confirmed free of contamination from mycoplasma, fungi, yeast, and bacteria.
| Species | Mouse |
| Cat.No | ABC-RC038Y |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Breast |
| Disease | Mouse breast cancer |
| Biosafety Level | 2 |
| Storage | Liquid Nitrogen |
| Product Type | Reporter Stable Cell Lines |
| Host Cell | 4T1 |
| Gene Info | RFP / Luciferase / HSV1-tk |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The 4T1/RFP-Luciferase HSV1-tk Stable Cell Line is an advanced murine breast cancer model integrating red fluorescent protein (RFP), luciferase bioluminescence, and HSV1-tk PET imaging reporters. This system enables simultaneous fluorescence microscopy (RFP), sensitive bioluminescent quantification (luciferase), and radiotracer-based anatomical imaging (HSV1-tk), providing three complementary modalities for comprehensive tumor monitoring. Ideal for metastasis studies, drug screening, and therapy evaluation, this cell line facilitates cross-validation across imaging platforms. Maintain in DMEM medium with appropriate selection agents to ensure stable triple-reporter expression in both in vitro and in vivo applications.