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Transfected Stable Cell Lines

Activin A Reporter Cell Line

  • For research use only

Cat No.

ABC-RC151F
Product Type

Reporter Stable Cell Lines
Cell Type

Epithelial
Species

Human
Host Cell

HEK293
Source Organ

Kidney
Disease

Normal
Storage

Liquid Nitrogen

Activin A Reporter Cell Line enables sensitive monitoring of TGF-beta/Activin signaling for stem cell, developmental, and drug discovery research.

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  • Activin A Reporter Cell Line
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Home | Transfected Stable Cell Lines | Reporter Stable Cell Lines | Activin A Reporter Cell Line

Description

ActRIIA (ACVR2A) and ActRIIB (ACVR2B) are members of the transforming growth factor β (TGF-β) receptor family, including activin A, activin B, BMP7, BMP9, BMP10, GDF1, GDF8 (myostatin), GDF11, and Nodal. ALK4 and ALK7 are principal type I TGF-β receptor family members for activin A and activin B, respectively. Bimagrumab is a human monoclonal antibody that can block the activin II type receptor (ActRII) to regulate skeletal muscle growth.Activin A Reporter Cell Line is a luciferase reporter gene cell line that uses Activin A as the agonist for activity detection (specifically for Activin A activity; does not differentiate between ACVR2A and ACVR2B). When Activin A binds to the receptor, it activates the signal pathway, leading to the expression of luciferase, with luciferase readings representing the activation effect of the signal pathway. Moreover, this activation effect can also be blocked by inhibitory antibodies such as Bimagrumab, making it suitable for evaluating the effects of related drugs in vitro.

Species

Human
Cat.No

ABC-RC151F
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Reporter Stable Cell Lines
Host Cell

HEK293

Application

  • For research use only

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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