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| Species | Human |
| Cat.No | ABC-KC0063 |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 100ug |
| Shipping Info | Ice Pack |
| Growth Conditions | 37 ℃, 5% CO2 |
| Storage | Store ALAS1 KO Cell Lysate At -20℃. Please Avoid Repeated Freeze-Thaw Cycles. |
| Product Type | CRISPR Knockout Cell Lysate |
| Host Cell | HEK293T |
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
For research use only