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| Species | Human |
| Cat.No | ABC-TC158D |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Eye |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Retinal Pigment Epithelium Cell Line |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
ARPE-19 cells are a widely recognized in vitro model in ophthalmic research, particularly for studying retinal pigment epithelium physiology, ocular drug transport, and retinal disease mechanisms. They are instrumental in modeling age-related macular degeneration (AMD), oxidative stress responses, and RPE-mediated phagocytosis of photoreceptor outer segments. Additionally, ARPE-19 supports transfection and gene expression studies, enabling exploration of pigmentation, retinal metabolism, and barrier function. However, ARPE-19 contains a mixture of mortal and immortal cell populations, and its gene expression profile differs from native RPE cells, therefore, careful experimental validation is advised when modeling retinal pathophysiology or evaluating therapeutic interventions.
