For research use only
| Cat No. | ABC-TC0066 |
| Product Type | Bovine Aortic Endothelium Cell Lines |
| Species | Bos Taurus |
| Growth Conditions | 37 ℃, 5% CO2 |
| Product Code | BAE; Bovine Aortic Endothelium-1 |
Bovine aortic endothelium. Derived from the aorta of a Friesian cow. Cells form sprouts after confluence.
BAE-1 (full form: Bovine Aortic Endothelium-1) is a bovine aortic endothelial cell line derived from the aortic tissue of a Friesian cow. The cells exhibit a cobblestone-like endothelial morphology and grow as adherent monolayers under standard culture conditions. Notably, BAE-1 cells form capillary-like sprouts upon reaching confluence, mimicking in vivo angiogenic behavior. These cells actively secrete proteoglycans, which are key components of the vascular extracellular matrix and play a role in endothelial signaling and vessel integrity. BAE-1 is persistently infected with Bovine Viral Diarrhea Virus (BVDV), a common ruminant virus that is non-pathogenic to humans but may influence experimental outcomes related to viral responses or immune activation. BAE-1 is non-tumorigenic and shows no metastatic behavior. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | BAE; Bovine Aortic Endothelium-1 |
| Species | Bos Taurus |
| Cat.No | ABC-TC0066 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Bovine Aortic Endothelium Cell Lines |
BAE-1 cells are widely used as an in vitro model for studying bovine vascular endothelium, angiogenesis, endothelial-matrix interactions, and proteoglycan biology. Their ability to form sprouts and secrete matrix components makes them suitable for examining vascular remodeling, endothelial permeability, and response to pro-angiogenic or inflammatory stimuli. Researchers also use BAE-1 for testing biomaterials, drug delivery systems, and viral infection dynamics in ruminants.
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