Bovine Brain Microvascular Endothelial Cells

Description

Bovine Brain Microvascular Endothelial Cells are endothelial cells derived from bovine brain microvessels, which constitute the core structural unit of the blood-brain barrier (BBB). Morphologically, these cells are typical paving stone-like polygonal or fusiform, with large and clear nuclei. They express endothelial markers such as CD31 and vWF, which are important for identifying their vascular endothelial characteristics and support their barrier-related phenotype within the BBB. Functionally, Bovine Brain Microvascular Endothelial Cells contribute to the selective permeability of the BBB and participate in neuroimmune regulation, including mediating interactions with immune cells under pathological or stimulus-induced conditions. At the molecular and cellular levels, these cells exhibit features closely associated with bovine brain vasculature endothelial function, while maintaining characteristic profiles of bovine endothelial cell surface markers that define their endothelial identity. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.