Home > Products > Tumor Cell Lines > Human Tumor Cell Lines >

Calu-3

Product Name

Calu-3

Price Get Quote
Product Code

CaLu-3; CALU-3; Calu 3; Calu3; CALU3

Cat.No

ABC-TC0111

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The Calu-3 cell line is a human lung cancer cell line that originates from human bronchial  submucosal glands. It stands out as one of the respiratory cell lines capable of forming polarized monolayers with tight junctions in vitro. Calu-3 monolayers exhibit closely apposed cuboidal and polygonal cells, characterized by microvilli on the apical surface and electron-dense areas near the upper parts of the intercellular junctions where tight junctions are typically found. These cells express ZO-1, a protein associated with tight junctions, as well as E-cadherin, an adherin protein. Calu-3 cells demonstrate notable transepithelial resistance (Rte) and display increased short-circuit current (Isc) in response to mediators.

 

Why choose Calu-3 from AcceGen?

Calu-3 cells possess high viability and are maintained in a sterile environment, ensuring they are free from mycoplasma contamination. These cells are carefully incubated under optimal conditions by skilled operators, and their quality is maintained through rigorous quality control measures.

Disease

Lung Cancer

Source Organ

Lung

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

Calu-3 cells have various applications in respiratory research. They are commonly used to model the airway epithelial barrier, providing valuable insights into lung-related studies. The utilization of this cell line holds immense value in the in vitro propagation of SARS-CoV-2, serving as an appropriate host for transfection purposes, and offering significant applications in the realms of cancer and toxicology research. Calu-3 cells also serve as a respiratory model for investigating the impact of gas concentrations, exposure time, biophysical stress, and biological agents on human airway epithelial cells. Moreover, they serve as a sensitive and efficient preclinical model for studying respiratory processes and diseases associated with oxygen- and ventilator-induced lung injury. Overall, Calu-3 cells offer significant potential for advancing our understanding of respiratory health and developing therapeutic interventions.

Growth Conditions

37 ℃, 5% CO2

Cell Type

Epithelial

Growth Mode

Adherent

Product Type

Human Lung Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
  • ONLINE INQUIRY
  • PRODUCT REVIEWS
We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time?

Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
Privacy Policy: AcceGen will never sell, rent, or share your personal information with any third parties without your express permission.
Reviews of Calu-3
AcceGen is always trying to do right by our customers and working hard to build a higher quality product.

Your email address will not be published.

AcceGen Scroll Top Button