For research use only
| Cat No. | ABC-TC0183 |
| Product Type | Human Lung Cancer Cell Lines |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Lung Small Cell Cancer |
| Product Code | CORL311 |
Explore COR-L311 to evaluate chemoresistance, tumor relapse mechanisms, and lung small cell carcinoma progression in patient-derived cancer models.
COR-L311 is isolated from a 63-year-old male patient with extensive disease and relapse after 3 cycles of chemotherapy treatment with eroposide, colchicine, methotrexate and vincristine. The growth mode of COR-L311 is characterized by large aggregates in suspension. Cytogenetic analysis reveals a complex karyotype with multiple chromosomal abnormalities, commonly associated with high genomic instability in small cell lung carcinoma (SCLC). COR-L311 cells demonstrate rapid proliferation and exhibit cellular responses to experimental agents, making them valuable for studying mechanisms of drug resistance and cellular sensitivity in vitro. They express POU2F3. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | CORL311 |
| Species | Human |
| Cat.No | ABC-TC0183 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Lung |
| Disease | Lung Small Cell Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Lung Cancer Cell Lines |
COR-L311 is widely used in scientific research and drug development. In experimental studies, it exhibits measurable responses to molecular perturbations, making it a useful tool for investigating drug response mechanisms and cellular pathways in SCLC. Researchers can study the effects of experimental treatments on growth and proliferation, analyze mechanisms of cellular resistance, and investigate pathways regulating drug response, providing insights into SCLC biology and resistance mechanisms.
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
