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DMS 153

Product Name

DMS 153

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Product Code

DMS-153; DMS153

Cat.No

ABC-TC0213

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

The DMS 153 cell line was derived from metastatic liver tissue obtained during autopsy from a patient afflicted with small cell carcinoma of the lung (SCLC) who had undergone cytoxan and methotrexate treatment. These cells exhibit tumorigenic properties in nude mice and secrete moderate amounts of calcitonin (CT) and calcitonin gene-related peptide (CGRP). Furthermore, they have been found to produce adrenocorticotropin (ACTH), bombesin (BN), 17 beta-estradiol, and oxytocin-neurophysin (OT-NP). DMS 153 cells express various cell surface antigens, including Leu 7, HLA-DR, My 23, the AML-1-99 defined antigen, and CR3 receptor, while also possessing receptors for bombesin (BN) and epidermal growth factor (EGF).

 

Why choose DMS 153 from AcceGen?

AcceGen’s DMS 153 cell line stands out for its robust features, boasting high viability and top-notch quality. These cells are carefully nurtured under ideal conditions and expertly cryopreserved. They are delivered in a sterile state, thoroughly screened to be mycoplasma-free, and their identity is confirmed through STR analysis, all part of AcceGen’s stringent quality control measures, making them a trusted and reliable choice for research applications.

Disease

Lung Small Cell Cancer

Source Organ

Lung

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

FOR RESEARCH USE ONLY

The DMS 153 cell line plays a pivotal role in cancer research, particularly in the study of small cell carcinoma of the lung (SCLC). Researchers utilize this cell line to identify novel biomarkers that can aid in the diagnosis and treatment of SCLC. Additionally, DMS 153 cells are instrumental in elucidating the effects of potential therapeutic strategies on cancer cells, including the induction of apoptosis, offering valuable insights into the development of more effective treatments for this aggressive form of lung cancer.

Growth Conditions

37 ℃, 5% CO2

Growth Mode

Semi-adherent

Product Type

Human Lung Cancer Cell Lines

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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